No, single page website aren’t useful for affiliate marketing out of the box as there will be no traffic driven to that website just by being online.
No, single page website isn’t useful for affiliate marketing out of the box or if you prefer domain cloaking. A single page hanging in the cyberspace is of no use as there will be no traffic to it.
If you can do a paid marketing to drive traffic and grab email addresses of users, it may be somewhat useful provided you can offer value on the landing page for readers to provide you with their email address. Otherwise pretty useless.
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